Serodiagnosis of chronic and acute Chagas' disease with Trypanosoma cruzi recombinant proteins: results of a collaborative study in six Latin American countries.

نویسندگان

  • Eufrosina S Umezawa
  • Alejandro O Luquetti
  • Gabriela Levitus
  • Carlos Ponce
  • Elisa Ponce
  • Diana Henriquez
  • Susana Revollo
  • Bertha Espinoza
  • Octavio Sousa
  • Baldip Khan
  • José Franco da Silveira
چکیده

An enzyme-linked immunosorbent assay to diagnose Chagas' disease by a serological test was performed with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity (99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase of T. cruzi infection.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 1  شماره 

صفحات  -

تاریخ انتشار 2004